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ALS
Information
Amyotrophic
Lateral Sclerosis (ALS), commonly known as Lou Gehrig's disease,
is a progressive neurodegenerative disease which attacks the
upper motor neurons of the brain and the lower motor neurons
in the spinal cord. These motor neurons control the movement
of voluntary muscles. When the motor neurons can no longer
send impulses to the muscles they begin to waste away, or
atrophy, causing muscle weakness and lack of function. Motor
neuron, or nerve cell death, makes it increasingly difficult
for the brain to control muscles or signal them to move. Symptoms
of ALS include twitching and cramping of muscles (called fasciculation),
loss of motor control in hands and arms, impaired use of the
arms and legs, weakness and fatigue, tripping and falling,
dropping things, slurred or thick speech and difficulty breathing
or swallowing.
In
most cases, ALS patients do not experience impaired intellectual
reasoning, vision or hearing. Eye and bladder muscles, along
with sexual function and drive, are not normally affected.
ALS can be diagnosed using a variety of tests and examinations,
including laboratory tests, muscle and nerve biopsy, spinal
tap, X-rays, MRI's and electrodiagnostic tests.
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